Skin Boosters vs Polynucleotides – What’s the Difference? | Old Swan Liverpool
At The Beauty Spot Liverpool, located in Old Swan, Liverpool, our clients frequently ask whether skin boosters or polynucleotides are better for rejuvenating the skin. Though both options enhance skin quality, they function in different ways and suit different goals. Here’s a clear comparison to help you understand which option may be best for you.
What Are Skin Boosters?
Skin boosters are injectable treatments that deliver hyaluronic acid (HA) and sometimes additional vitamins or amino acids directly into the skin’s dermis.
How They Work:
Hyaluronic acid attracts and retains water, providing deep hydration
Improves skin plumpness, smoothness, and elasticity
Stimulates some collagen production but primarily works as a hydrator
Examples: Profhilo, Profhilo Structura, Revs PRO 32
Best For:
Dry or dehydrated skin
Early fine lines and loss of skin glow
Clients wanting a refreshed, plumper appearance without changing facial shape
Results:
Usually require 2–3 sessions
Last around 6 months depending on lifestyle and skin condition
What Are Polynucleotides?
Polynucleotides are an advanced type of skin regenerative treatment. They are made from purified DNA fragments, which act as bio-stimulators to regenerate and repair the skin from within.
How They Work:
Stimulate fibroblasts to produce more collagen and elastin
Improve microcirculation for better oxygen and nutrient delivery
Reduce oxidative stress, slowing the ageing process
Actively repair skin damage and improve tissue structure
Examples: Plenhyage (our top recommendation), Lumi Eyes, Plinest
Best For:
Skin with signs of ageing or sun damage
Acne scarring or post-inflammatory skin texture issues
Under-eye rejuvenation for dark circles, fine lines, and hollowness
Long-term skin health improvement
Results:
Usually require 2–4 sessions
Last up to 9 months, with cumulative benefits over time
Key Differences – Skin Boosters vs Polynucleotides
Feature Skin Boosters Polynucleotides
Main Ingredient Hyaluronic Acid Purified DNA fragments
Primary Action Hydration & plumping Regeneration & repair
Collagen Stimulation Mild Strong
Best For Dryness, early sign of wrinkles Scarring, ageing, skin repair
Under-Eye Use Yes, some products Yes,highly effective
Results Duration ~6 months ~9 months
Examples Profhilo, Revs PRO 32 Plenhyage, Lumi Eyes, Plinest
Which Treatment Is Right for You?
Choose Skin Boosters if you want a fast hydration boost and improved skin glow, especially for events or seasonal refreshes.
Choose Polynucleotides if you want long-term skin regeneration, treatment for scarring, or under-eye rejuvenation with structural improvements.
At The Beauty Spot Liverpool in Old Swan, we offer both treatments and often recommend them in combination for maximum results — hydrating the skin with boosters while regenerating and repairing it with polynucleotides.
